C5-H4-N4-O2. [2], Studies reported in 2008, based on 12C/13C isotopic ratios of organic compounds found in the Murchison meteorite, suggested that xanthine and related chemicals, including the RNA component uracil, have been formed extraterrestrially. Loomis, R. Coimbra, L.J. Xanthines vormen een groep alkaloïden die veel gebruikt worden vanwege de stimulerende effecten en als bronchodilatoren, vooral in het behandelen van astma. Chemically, xanthine is a purine. xanthine - crystalline oxidation product of the metabolism of nucleoproteins; precursor of uric acid; found in many organs and in urine organic compound - any compound of … Xanthine oxidase is a flavoprotein that contains molybdenum, nonheme iron, and labile sulfur. De tekst is beschikbaar onder de licentie. xanthine. Bij hoge dosis treedt misselijkheid op, die niet met anti-braakmiddelen te bestrijden is. Baraldi, M.A. Examples of how to use “xanthine” in a sentence from the Cambridge Dictionary Labs [2] Deze stoffen werken zowel als, De verschillende verbindingen vertonen een grote spreiding aan activiteit ten gevolge van het grote aantal subtypes van de receptor. xanthine[′zan‚thēn] (organic chemistry) C5H4N4O2 A toxic yellow-white purine base that is found in blood and urine, and occasionally in plants; it is a powder, insoluble in water and acids, soluble in caustic soda; sublimes when heated; used in medicine and as a chemical intermediate. Siegel (RICHARDSON-VICKS, INC), Constantin Koulbanis, Claude Bouillon, Patrick Darmenton (L'Oreal), O.H. In het centraal zenuwstelsel stimuleren zij alertheid, het ademhalingscentrum, en worden ze toegepast ter bestrijding van apneu bij kinderen. Methylated xanthine compounds such as caffeine, theobromine, and theophylline are used for their bronchodilator effects. Shamim, W.L. Choi, M.T. Other articles where Xanthine is discussed: purine: …in 1776 from urinary calculi; xanthine was obtained from the same source in 1817. Deree, J.O. Daly, M.T. From French xanthine, ultimately from Ancient Greek ξανθός (xanthós, “yellow”), because xanthine is yellowish-white. Noun. [2] In high doses, they can lead to convulsions that are resistant to anticonvulsants. Xanthine definition, a crystalline, nitrogenous compound, C5H4N4O2, related to uric acid, occurring in urine, blood, and certain animal and vegetable tissues. There is a genetic disease of xanthine metabolism, xanthinuria, due to deficiency of an enzyme, xanthine dehydrogenase, needed to … A xanthine, also spelled xanthin, is one of a group of alkaloids which include caffeine, theophylline, and theobromine, a precursor of uric acid. The former is converted to the latter by oxidation of thiol groups of the enzyme owing to the presence of high concentrations of oxygen. Some are used medicinally to treat asthma and other respiratory conditions. Methylxanthine definition is - a methylated xanthine derivative (such as caffeine, theobromine, or theophylline). The methylated xanthine compounds caffeine, theobromine, and theophylline and their derivatives are used in medicine for their bronchodilator effects. Xanthine oxidase (xanthine dehydrogenase) deficiency, type I, is an uncommon autosomal recessive disorder characterized by the excretion of urinary xanthine and hypoxanthine as the chief end products of purine metabolism, and by low serum and urinary uric acid levels. Verbindingen waarvan het centrale deel van het molecuul gevormd wordt door de twee ringen in xanthine, worden aangeduid als xanthines. Xanthine, vroeger ook aangeduid als xanthinezuur en volgens de IUPAC 3,7-dihydro-purine-2,6-dion, is een purinebase die voorkomt in de meeste organen en weefsels van praktisch alle organismen. [2] Methylxanthines are metabolized by cytochrome P450 in the liver. Gemethyleerde xanthinederivaten zijn cafeïne (in koffie en gewone thee), paraxanthine, theofylline en theobromine (vooral in chocolade). The xanthine alkaloids include caffeine, theobromine, and theophylline, and are well-known components of tea (Camellia sinensis), coffee (Coffea arabica), cola ingredients (Cola spp. Methylxanthines stimuleren de afgifte van pepsine en maagzuur. It is the responsibility of the Respiratory Therapist to learn about the drug class. Deze zeldzame erfelijke aandoening wordt xanthinuria genoemd. Chemical Name. Deze pagina is voor het laatst bewerkt op 23 nov 2020 om 10:32. [13][14] In August 2011, a report, based on NASA studies with meteorites found on Earth, was published suggesting xanthine and related organic molecules, including the DNA and RNA components adenine and guanine, were found in outer space. 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